Many cast and crew have worked on other important science fiction films and television. The following are probably the major science fiction series, with a simple guide to who to look out for.
- Star William Shatner's first acting job was in a Canadian theatre group headed by Barry Morse (Victor Bergman)
- Martin Landau (John Koenig) was considered for the role of Spock, but declined in order to do Mission: Impossible (shot on an adjacent stage to Star Trek at Paramount Studios).
- Joan Collins (Kara, Mission Of The Darians) was a guest star in the episode "City On The Edge Of Forever" (1967).
- Karl Held (Jerry Travis, The Immunity Syndrome) was a guest star in the episode "The Return Of The Archons" (1967, credited as Christopher Held). Thanks to Dana Lubich.
- Writer Art Wallace (Siren Planet) wrote the episodes "Obsession" (1967) and "Assignment Earth" (1968)
- Fred Freiberger (Year 2 producer/ writer) produced the third and final series of Star Trek (1969).
- Kathryn Leigh Scott (Yesta, Dorzak) was a guest star in Who Watches The Watchers, 1989
- Carolyn Seymour (Eva, Seance Spectre) was a guest star in Contagion, 1989, First Contact, 1991, Face Of The Enemy, 1993, and, in Star Trek Voyager, Eye Of The Needle, 1995, Cathexis, 1995, Persistence of Vision, 1995
- Jeremy Kemp (Queller, Voyager's Return) was a guest star in Family, 1990.
- Nick Tate (Alan Carter) was a guest star in the episode Final Mission (1990), and in the Star Trek Deep Space Nine episode Honour Among Thieves (1998). He was considered for the role of Quark in Deep Space Nine (1993).
Some British stations broadcast Space: 1999 at the same time as Dr Who, then at the height of its success with Tom Baker as the Doctor. Inevitably Space: 1999 ratings were dented by such strong established competition.
- Patrick Troughton (Archon, The Dorcons) was the second actor to play the Doctor, 1966-1969, reprised in 1973 and 1984
- Peter Cushing (Raan, Missing Link) played the Doctor in the film, Daleks Invasion Earth 2150 AD, 1966
- Zienia Merton (Sandra) was a guest star in the story Marco Polo, 1964.
- Prentis Hancock (Paul Morrow) was a guest star in "Spearhead From Space", 1970, "Planet Of The Daleks", 1973, "Planet Of Evil", 1975, and "The Ribos Operation", 1978
- Catherine Schell (Maya) was a guest star in the episode City Of Death, 1979
- Alibe Parsons (Alibe) was a guest star in "Mindwarp", 1986.
- Alf Joint (Steiner, Breakaway and Overseer, The Metamorph) was a stuntman on many episodes.
- Terry Walsh (rescue Eagle pilot, Mark Of Archanon, and Scotsman, Journey To Where) was a stuntman in numerous episodes, 1968-1979
- Bernard Kay (mutant, New Adam new Eve) was a guest star in Dalek Invasion of Earth, 1964, The Crusades, 1965, The Faceless Ones, 1967, Colony In Space, 1971
- Jeremy Young (Jack Bartlett, Bringers Of Wonder) was a guest star in An Unearthly Child, 1963 and Mission To The Unknown, 1965
- Kevin Stoney (Talos, Last Enemy) was a guest star in The Dalek Master Plan, 1966, The Invasion 1968 and Revenge Of The Cybermen, 1975
- Bernard Cribbins (Brian's voice, Brian The Brain) was in the film, Daleks Invasion Earth 2150 AD, 1966, and in the TV series Dr Who in 2007.
- Michael Sheard (Dr Darwin King, Dragon's Domain) was a guest star in The Ark, 1966, Mind Of Evil, 1971, Pyramids Of Mars, 1975, the Invisible Enemy, 1977, Castrovalva, 1981, Remembrance Of The Daleks, 1988
- Roy Stewart (alien, The Metamorph) was a guest star in Tomb Of The Cyberman, 1967, and Terror Of The Autons, 1971
- Philip Madoc (Gorski, Breakaway) was a guest star in War Games, 1969, The Krotons, 1969, Brain of Morbius (1976), The Power Of Kroll, 1978
- Julian Glover (Jarak, Alpha Child) was a guest star in The Crusades, 1969, and City Of Death, 1979
- Nick Hobbs (Clive Kander, Bringers Of Wonder) was a guest star in Mind Of Evil, 1971, The Curse of Peladon, 1972, and the Monster Of Peladon, 1974
- Gareth Hunt (pilot, Guardian Of Piri) was a guest star in Planet Of The Spiders, 1974
- Alan Harris (Alphan, many Year 1 episodes) was a guest star in Face Of Evil, 1963
- Max Faulkner (Ted Clifford, Ring Around The Moon) was a guest star in The Monster of Peladon, 1974, Planet Of The Spiders, 1974, Android Invasion, 1975, The Invasion of Time, 1978,
- Robert Russell (Hadin, Mission Of The Darians) was a guest star in Terror of the Zygons, 1975
- Roy Boyd (Lustig, Immunity Syndrome) was a guest star in The Hand Of Fear, 1976
- John Lorimore (Smitty, Black Sun) was a guest star in Masque of Mandragora 1976
- Brendon Price (security guard, Catacombs Of The Moon) was a guest star in Face Of Evil, 1977
- Gregory De Polnay (Pete Garforth, Lambda Factor) was a guest star in The Robots Of Death, 1977
- Godfrey James (Alien Transport, Rules Of Luton) was a guest star in Underworld, 1978
- Tony Osoba (security guard, Space Warp) was a guest star in Destiny Of The Daleks, 1979 and Dragonfire, 1987
- Geoffrey Bayldon (Number 8, One Moment Of Humanity) was a guest star in Creature from the Pit, 1979
- Annie Lambert (operative, various episodes) was a guest star in Four To Doomsday 1981
- Isla Blair (Female Alien, War Games and Carla, Journey To Where) was a guest star in King's Demons, 1983
- Paul Jerrico (Security guard, Dorzak) was a guest star in Arc Of Infinity, 1983
- Dallas Adams (Sam, Lambda Factor) was a guest star in "Planet Of Fire", 1984.
- John Alkin (Andy Johnson, Mark Of Archanon) was a guest star in "Planet Of Fire", 1984
- Brian Blessed (Rowland, Death's Other Dominion and Mentor, The Metamorph) was a guest star in Mindwarp (1986)
- Harry Fielder (George, Seance Spectre, also in Lambda Factor, Immunity Syndrome and The Dorcons) was an extra in The Wheel in Space (1968), Planet of the Spiders (1974), Revenge of the Cybermen (1975), The Seeds of Doom (1976), The Deadly Assassin ( 1976), The Face of Evil (1977), The Invisible Enemy (1977), The Ribos Operation (1978) , The Armageddon Factor (1979), Meglos (1980), Castrovalva (1982)
- Roy Marsden (Crael, Devil's Planet) was a guest in Smith and Jones (2007).
- Johnny Byrne (writer) wrote the episodes The Keeper Of Traken, 1981, Arc Of Infinity, 1983, Warriors Of The Deep, 1984
- Pip and Jane Baker (writers, A Matter Of Balance) wrote the episodes Mark Of The Rani, 1985, Trail Of A Time Lord part 3, 1986, Time & The Rani, 1987
- Terence Dicks (writer, The Lambda Factor) was script editor from 1968-1974 and wrote many episodes.
- Dennis Spooner (writer, Alien Attack scenes) was script editor from 1964-1965
- Martin Bower (model-maker) made models for the series in 1978.
- Sarah Douglas (B in A B Chrysalis) was a guest star in Deathwalker, 1994
- Roy Dotrice (Simmonds, Breakaway and Earthbound) was a guest star in Fall Of Night, 1995
- Aubrey Morris (Petros, Mission Of The Darians) was a guest star in Exogenesis, 1996
- Carolyn Seymour (Eva, Séance Spectre) was a guest star in Endgame, 1997
- Ian McShane (Zoref, Force Of Life) was a guest star in the TV movie River Of Souls (1998)
- George Lucas originally approached Brian Johnson in 1976 to do the special effects for the first Star Wars film. Johnson was busy with Space: 1999 Year Two, but in 1979 he was in charge of effects for the sequel, The Empire Strikes Back.
- The standard of effects in Space: 1999 was a stated benchmark for the special effects in Star Wars. Lucas insisted the models and explosions should be better than seen on the television series.
- The early design for the Millenium Falcon was vetoed by George Lucas as it closely resembled the Space: 1999 Eagle (see Robert Brown's detailed Star Wars ship commentaries: http://www.synicon.com.au/sw/br/tantive.htm and http://www.synicon.com.au/sw/mf/concep2.htm). Early designs and concept models featured side legs, rear engines, side docking ports and a cone shaped nose that looked even more like the Eagle. A hammerhead was added to the model and it appeared on screen as the Blockade Runner, the first ship seen in the film. The Millenium Falcon was redesigned as a saucer shaped craft, the rush job creating serious inconsistencies between sets and model.
- Dave Prowse (Creature, Beta Cloud) starred as Darth Vader in the first three films (James Earl Jones supplied the voice)
- Peter Cushing (Raan, Missing Link) starred as the Grand Moff Tarkin in the first film.
- Richard Le Parmentier (Sam Malcolm, Dorzak) played a small role as Admiral Motti in the first film.
- Drewe Henley (Joe Ehrlich, Bringers Of Wonder) played a small role as Red Leader in the first film.
- Angus MacInnes (Jelto, Devil's Planet) played a small role as Gold Leader in the first film.
- Shane Rimmer (Kelly, Space Brain) played a minor role as a technician in the first film.
- Jack Klaff (security guard, Seed Of Destruction) played a minor role in the briefing room scene in the first film.
- Christine Hewett (female Kaldorian, Earthbound) played a minor role as an alien in the Cantina sequence in the first film.
- Pam Rose (Command Center Operative, many Year 2 episodes) played a minor role as an alien (named Leebub Sirln) in the Cantina sequence in the first film.
- Gerald Staddon (Male Mute, Mission Of The Darians) played an Ewok in Return of The Jedi (1983)
- David Tomblin (director) was assistant director on The Empire Strikes Back and Return Of The Jedi.
- Paul Weston (stuntman, various episodes) was a stunt coordinator on Return Of The Jedi.
- Jack McKenzie (technician, The Last Sunset) played Cal Alder in The Empire Strikes Back
- Michael Culver (Pete Irving, Guardian Of Piri) appeared as Captain Needa in The Empire Strikes Back (1980)
- Michael Sheard (Dr Darwin King, Dragon's Domain) appeared as Admiral Ozzel in The Empire Strikes Back (1980).
- Julian Glover (Jarak, Alpha Child) appeared as General Veers in The Empire Strikes Back (1980)
- Alf Joint (Steiner, Breakaway and Overseer, The Metamorph) was a stuntman on Return of The Jedi (1983)
- Alan Harris (Alphan, many Year 1 episodes) was Leia's rebel escort and a Stormtrooper in Star Wars (1977), Bespin Guard and C3PO stand-in and body double for Harrison Ford in the carbonite in The Empire Strikes Back (1980), C3PO stand-in in Return Of The Jedi, and stand-in for Terence Stamp in The Phantom Menace (1999).
- Quinton Pierre (security guard Quinton or Pierce, both Years) was a Bespin Guard in The Empire Strikes Back (1980) and stand-in for Billy Williams
- Norwich Duff (Texas City Operative, Journey To Where) appeared as a rebel officer in The Empire Strikes Back (1980)
- Jenny Cresswell (Alphan, various episodes) appeared as Han Solo's girlfriend in a cut scene of Star Wars (1977)
- Harry Fielder (George, Seance Spectre, also in Lambda Factor, Immunity Syndrome and The Dorcons) was a Death Star Trooper in Star Wars (1977)
- Brian Blessed (Rowland, Death's Other Dominion and Mentor, The Metamorph) appeared as Boss Nass in The Phantom Menace (1999).
- Christopher Lee (Zantor, Earthbound) appeared as Count Dooku in Attack Of The Clones (2002) and Revenge Of The Sith (2005).
- Brian Johnson and Nick Allder (SFX directors) were special effects directors of the first and second films.
- Martin Bower (model-maker) made models for the first film.
- Emma Porteus (Year 2 costume designer) designed costumes for the first sequel, Aliens (1986).
- Alibe Parsons (Alibe) was a nurse in Aliens (1986)